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Reference values for 99mTc-MAG3 renography determined in healthy, potential renal donors
Thomas D Clausen1, Inge-Lis Kanstrup, Jens Iversen
1Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Herlev, Denmark. tdclausen@mail.dk
Background:
Reference values for 99mTc-MAG3 renography were determined and the influence of sex and age (< 50/ > or = 50 years) was elucidated.
Methods:
Sixty-eight potential renal donors were evaluated by renography among other tests. Through examination of their records 41 healthy subjects with a normal renal arteriography were included in this study and the reference values of the functional distribution (the split function, SF), the time to peak renal parenchymal activity (Tmax) and the residual activity (RA) were calculated.
Results:
For Tmax there was no significant influence of sex or age. Mean RA increased significantly with age (20.5 vs. 23.2%, P = 0.03), but no difference was found between sexes. Mean SF (right kidney) was significantly higher among males.
Conclusions:
When a diuresis of at least 2 ml min-1 is demanded we found the following normal ranges: SF > 41%, Tmax < 4.3 min and RA < 33.7%.