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Updated: Aug 14, 2026
07:17
Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
[Nutrition, bone disease and alcoholic cirrhosis]
M A Escalante Boleas1, R Franco Vicario, L Cubas Largacha
1Servicio de Medicina Interna, Hospital de Basurto.
Anales De Medicina Interna (Madrid, Spain : 1984)
|December 19, 2002
Summary
This study found a high prevalence of osteopenia and osteoporosis in alcoholic cirrhotic males aged 45-65. Nutritional status alone was not found to be a direct cause of bone loss in these patients.
Area of Science:
- Hepatology
- Endocrinology
- Bone Metabolism
Context:
- Alcoholic cirrhosis is associated with various complications.
- Bone density loss is a concern in patients with chronic liver disease.
- Understanding the factors contributing to bone disease in this population is crucial.
Purpose:
- To determine the prevalence of osteopenia and osteoporosis in alcoholic cirrhotic males aged 45-65.
- To investigate the role of nutritional status in bone mass reduction in hepatic disease.
Summary:
- A descriptive study of 52 alcoholic cirrhotic males (45-65 years) evaluated bone mineral density using dual-energy X-ray absorptiometry.
- Prevalence of osteopenia and osteoporosis was 58%.
- Nutritional parameters, including body fat percentage, were assessed but showed no significant correlation with bone mass loss.
Impact:
- Highlights a high prevalence of bone disease in alcoholic cirrhotic males.
- Suggests that nutritional status, as an isolated factor, may not be the primary driver of bone loss in this group.
- Emphasizes the need for further research into the multifactorial causes of bone disease in alcoholic liver disease.
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