Related Experiment Videos
Colorectal polyps and other precursor lesions. Need for an expanded view
1Mayo Clinic, Department of Laboratory Medicine and Pathology, 200 First Street SW, Rochester, MN 55905, USA. burgart.lawrence@mayo.edu
Abstract:
The traditional understanding of adenomas serving as precursors for a homogeneous group of adenocarcinomas is being assailed from all sides. Clearly, the relationship between precursor lesions and adenocarcinomas with defective DNA mismatch repair is much more complex and appears to include right-sided hyperplastic polyps as precursor lesions in some cases. Additional data will be forthcoming regarding this risk of adenocarcinoma development in right-sided hyperplastic polyps, both through defective DNA mismatch repair and methylation of the MGMT gene. This will likely be accompanied by an attempt to reclassify at least some larger hyperplastic polyps as serrated adenomas either on subtle morphologic or molecular grounds.
Related Concept Videos
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Endoscopic Procedures II: Colonoscopy
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...