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Macrocephaly and epidural involvement of T-cell acute lymphoblastic leukemia
Tang Her Jaing1, Po Cheng Hung, Iou Jih Hung
1Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan.
Pediatric Neurology
|December 31, 2002
Abstract:
We describe a 2-year-old female who presented with macrocephaly and anemia. Magnetic resonance imaging revealed a diffusely enhancing epidural lesion over the sagittal frontoparietal region. Bone marrow examination confirmed the diagnosis of T-cell acute lymphoblastic leukemia. Induction chemotherapy led to hematologic remission and neuroimaging resolution of the mass. This report suggested macrocephaly could be a rare and early manifestation of leukemia in children.