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Expression, structure-function, and molecular modeling of vitamin D P450s

J L Omdahl1, E V Bobrovnikova, A Annalora

  • 1Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131-5221, USA. jomdahl@salud.unm.edu

Journal of Cellular Biochemistry
|January 10, 2003
PubMed
Summary

Vitamin D(3) requires specific enzymes for activation and inactivation. This study details how rat cytochrome P450C24 (CYP24) degrades active vitamin D metabolites, focusing on its catalytic actions and active site mutations.

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