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Updated: Sep 27, 2026

Generation of Monocyte-Derived Dendritic Cells with Differing Sialylated Phenotypes
Published on: October 20, 2023
Diversity of the human erythrocyte membrane sialic acids in relation with blood groups
Tatiana Bulai1, Daniela Bratosin, Alexandre Pons
1Laboratoire de Glycobiologie Structurale et Fonctionnelle, CNRS Unité Mixte de Recherche No. 8576, Université des Sciences et Technologies de Lille, Bâtiment C9, 59655 Cedex, Villeneuve d'Ascq, France.
Abstract:
The composition of the human erythrocyte membrane (RBC) glycoprotein- and glycolipid-bound sialic acids of A, B, AB and O type donors was studied using a new method (Zanetta et al., Glycobiology 11 (2001) 663-676). In addition to Neu5Ac as the major compound, Kdn, Neu5,9Ac(2), Neu5,7Ac(2), Neu (de-N-acetylated-Neu5Ac), Neu5Ac8Me, Neu5Ac9Lt, Neu4,5Ac(2), Neu5,8Ac(2)9Lt and Neu5Ac8S were characterised. Among these different compounds, Neu5Ac8Me, Neu5Ac9Lt, Neu4,5Ac(2), Neu5,8Ac(2)9Lt and Neu5Ac8S have never been described and quantitatively determined before in human tissues or cells. Neu5Gc and its O-alkylated or O-acylated derivatives were not detected.
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