Related Experiment Videos
Bringing classical embryology to C elegans gastrulation
Rachel E Dawes-Hoang1, Jennifer A Zallen, Eric F Wieschaus
1Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA.
Developmental Cell
|January 18, 2003
Abstract:
In a recent paper, Lee and Goldstein develop an explant assay that recapitulates key aspects of gastrulation in C elegans and permits classical embryological manipulations. The resulting detailed analysis of cell behavior will ultimately extend to broader issues, such as, whether morphogenesis can be described as the sum of single-cell events or if unique phenomena emerge at the multicellular level.