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[JTc prolongation in hypertrophic cardiomyopathy amd arterial hypertension]

Daiva Emilija Rekiene1

  • 1Kauno medicinos universiteto Kardiologijos institutas, Sukileliu 17, 3007 Kaunas.

Medicina (Kaunas, Lithuania)
|January 21, 2003
PubMed

Insights

Transesophageal pacing of the left atrium detects pathological long JTc intervals in patients with hypertrophic cardiomyopathy and arterial hypertension, even when resting ECGs appear normal. This method aids in identifying sudden death risk factors.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Sudden Cardiac Death Research

Background:

  • Pathological prolongation of QTc and JTc intervals is a significant risk factor for sudden cardiac death.
  • Electrocardiogram (ECG) investigations, particularly during stress or pacing, can reveal critical cardiac information.

Purpose of the Study:

  • To identify factors contributing to sudden death in patients with hypertrophic cardiomyopathy (HCM) and arterial hypertension (AH).
  • To evaluate electrocardiographic changes, specifically JTc interval variations, using transesophageal pacing of the left atrium (TPL A) in these patient groups and healthy individuals.

Main Methods:

  • Transesophageal pacing of the left atrium was performed on 12 healthy individuals, 12 patients with arterial hypertension, and 13 patients with hypertrophic cardiomyopathy.
  • Pacing was conducted at three different rates (80, 100, and 130 bpm) for 3 minutes each.

Main Results:

  • No JTc interval prolongation was observed in the control group.
  • JTc interval prolongation ( > 0.35 s) was detected in 3 patients with arterial hypertension and 3 patients with hypertrophic cardiomyopathy during pacing.
  • Prior to pacing, prolonged JTc intervals at rest were noted in 5 hypertrophic cardiomyopathy patients and 1 arterial hypertension patient.

Conclusions:

  • Transesophageal pacing of the left atrium is effective in uncovering pathological long JTc intervals in patients with arterial hypertension and hypertrophic cardiomyopathy.
  • This pacing method can identify individuals at risk for sudden death when their resting electrocardiograms do not show JTc interval prolongation.
Abstract

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