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Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells
10:18

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[Effection of children airway foreign bodies on blood acid-base disturbances]

L Tao1, X Peng

  • 1Department of Otolaryngology, Children Hospital of Hunan, Changsha 410007.

Lin Chuang Er Bi Yan Hou Ke Za Zhi = Journal of Clinical Otorhinolaryngology
|January 25, 2003
PubMed

Insights

Children with airway foreign bodies often experience blood acid-base disturbances, primarily simple or mixed metabolic acidosis, frequently with a high anion gap (AG). This highlights a significant physiological impact of airway obstruction in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Clinical Chemistry
  • Emergency Medicine

Context:

  • Airway foreign body aspiration is a common pediatric emergency.
  • Foreign body aspiration can lead to significant respiratory compromise and systemic effects.
  • Understanding the metabolic consequences is crucial for timely diagnosis and management.

Purpose:

  • To investigate the prevalence and types of blood acid-base disturbances in children with airway foreign bodies.
  • To compare acid-base status between children with and without airway foreign bodies.
  • To identify specific patterns of acid-base imbalance associated with airway foreign body ingestion.

Summary:

  • Fifty children with airway foreign bodies were compared to 50 healthy controls.
  • Blood gas and electrolyte levels, including anion gap (AG), were analyzed.
  • Significant differences in blood gas and potassium levels were observed, with a high prevalence of metabolic acidosis (simple and mixed) and high AG in the affected group.

Impact:

  • Airway foreign bodies can induce significant acid-base disturbances in children.
  • Metabolic acidosis, particularly high anion gap metabolic acidosis, is a common complication.
  • Findings emphasize the need for comprehensive metabolic assessment in pediatric patients with suspected airway foreign bodies.
Abstract

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