Related Experiment Video
Updated: Aug 10, 2026
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
[The immunohistochemistry and clinic study on surgical margin of laryngeal cancer]
Objective:
To probe into the safe incisal range of removing laryngectomy cancer determined from the albumen balance of cells.
Method:
LSAB or SABC of immunohistochemistry was applied, and three groups of samples with cancer tissue, nearby cancer tissue and distal cancer tissue of 36 primary laryngectomy cancer were tested by antibodies p16, p21, TGF-beta 1, PCNA and EGFR.
Result:
The difference of the positive rate with the five antibodies between the cancer group and the two side incisal group were very notable with P < 0.01 or P < 0.05, but which between nearby cancer tissue and distal cancer tissue were not notable with P > 0.05. The differences of the positive rates with 5 antibodied between high differentiation group and low differentiation group were notable with P < 0.05, and P < 0.05 with PCNA in the group whether the lymphonodi cervicales transmitted or not. The incisals for all the cases are beyond 5 mm, the recurerence rate is 3%.
Conclusion:
The 5 mm incisal for laryngectomy cancer is appropriate on the albumen cevel of cells.
