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How many lethal alleles?
Daniel L Halligan1, Peter D Keightley
1Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT, Edinburgh, UK.
Trends in Genetics : TIG
|January 28, 2003
Abstract:
Knowledge of the frequency of lethal mutant alleles in a population is important for our understanding of population genetics and evolution, and yet there have been few attempts to measure their number in wild populations. A new study has revealed unexpectedly low numbers of segregating lethal alleles in two species of fish. More experiments are needed, however, to know whether this result is general.