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Quantitative assessment of tumor oxygen dynamics: molecular imaging for prognostic radiology
Ralph P Mason1, Sophia Ran, Philip E Thorpe
1Department of Radiology, U.T. Southwestern Medical Center, Dallas, Texas, USA. Ralph.Mason@UTSouthwestern.edu
Journal of Cellular Biochemistry. Supplement
|January 29, 2003
Abstract:
One of the fundamental molecules governing the survival of mammalian cells is oxygen. Oxygen has gained particular significance in tumor developmental biology and oncology. An increasingly diverse array of methods is now available to characterize tumor oxygenation. This Prospect will consider a new method, Fluorocarbon Relaxometry using Echo planar imaging for Dynamic Oxygen Mapping (FREDOM), which we have recently developed for oximetry, examine application to a specific therapeutic example and place this technique in the context of other approaches.