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Updated: Sep 27, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
[Experimental study on repair of cricoid cartilage defect with cartilage grafts in rabbits]
1Department of Otorhinolaryngology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038.
Objective:
To investigate the effect of free cartilage fragment in repair of cricoid cartilage defect.
Method:
One-third of cricoid cartilage was cut and repaired with free thyroid cartilage fragment and pedicled cartilage in rabbits. The pathological changes of the cartilages were observed.
Result:
1. The free thyroid cartilage fragments were absorbed in two months, and were replaced by scars. 2. The pedicled cartilage fragments were not absorbed and healed with the cricoid cartilage. 3. No evidence of growth impairment of surgery-induced cricoid cartilage was observed.
Conclusion:
In rabbits, both free cartilage fragments and pedicled cartilage fragments could repair the defect of cricoid cartilage effectively.
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