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Thyroid-hormone-induced phosphate absorption in Aplysia californica gut is mediated through protein synthesis
George A Gerencser1, Kuuleialoha M Cornette, Jianliang Zhang
1Department of Physiology and Functional Genomics, College of Medicine, Box 100274 JHMHC, University of Florida, Gainesville, FL 32610, USA. gag@phys.med.ufl.edu
Canadian Journal of Physiology and Pharmacology
|February 5, 2003
Abstract:
The mucosal membranes of Aplysia californica forgut epithelia contain a sodium-phosphate symporter that is stimulated by triiodothyronine. Actinomycin D, puromycin, or cycloheximide inhibited the triiodothyronine-stimulated phosphate absorption. It appears that thyroid hormone manifests its effects on phosphate absorption in the A. californica gut through protein synthesis.