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Updated: Sep 27, 2026

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
Published on: July 15, 2019
[Detection of serum antibody of coxsackievirus A24 variant]
Objective:
To observe the serum antibody in residents after outbreak of acute hemorrhagic conjunctivitis (AHC) caused by coxrackievirus (CA24 v).
Methods:
The serum was diluted in 1:10 and mixed with 100 TCID50 CA24 v in volume. The same the mixture was incubated 1 hour in 37 degrees C and then observed for cytopathic changes of the infected HeLa cells.
Results:
The post-epidemic antibody positive rate in residents was 49.67% and in 19-25 age group was about 69.49%. It had significant difference statistically (P < 0.01).
Conclusion:
The raising of CA24 v antibody level in residents was relevent with age. May be it was caused by the opporturnities of taking part in social activities in different age groups.

