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Medicinal chemistry of adenosine A1 receptor ligands
Willem Soudijn1, Ineke van Wijngaarden, Ad P IJzerman
1Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, P.O. Box 9502, The Netherlands.
Current Topics in Medicinal Chemistry
|February 7, 2003
Abstract:
In this review the latest developments in ligand design for the adenosine A(1) receptor are summarized. Novel series of agonists and antagonists are discussed, leading to the conclusion that ligands truly selective for the human adenosine A(1) receptor are still scarce.