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Ferritin intestinal absorption.

J Balasch, J Ibáñez, L Palacios

    Revista Espanola De Fisiologia
    |March 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Ferritin provides iron with good absorption rates in both normal and iron-deficient rats. Anemic rats show lower intestinal iron stores, indicating increased iron uptake from the gut into the bloodstream.

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    Area of Science:

    • Biochemistry
    • Physiology
    • Nutritional Science

    Background:

    • Ferritin is the primary intracellular iron-storage protein.
    • Iron absorption is a critical physiological process regulated by various factors.
    • Understanding iron bioavailability from different sources is essential for managing iron deficiency.

    Purpose of the Study:

    • To evaluate ferritin as a source of dietary iron.
    • To assess iron absorption rates from ferritin in vivo.
    • To compare iron absorption in normal and iron-deficient animal models.

    Main Methods:

    • In vivo iron absorption technique was employed in rats.
    • Ferritin was utilized as the iron source.
    • Iron levels in the intestinal wall were measured.

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    Main Results:

    • Ferritin demonstrated a good iron absorption rate in normal rats.
    • Iron absorption from ferritin was comparable in iron-deficient animals.
    • Anemic rats exhibited lower iron concentrations in the intestinal wall compared to normal rats.

    Conclusions:

    • Ferritin is an effective source of bioavailable iron.
    • Iron absorption from ferritin is efficient, even in states of iron deficiency.
    • The intestinal tract actively draws iron from the lumen into circulation when anemic.