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Differential gene expression in retina of myopic chicken eyes using mRNA differential display
1Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Purpose:
To study differentially expressed genes in retina of experimental myopic chicken.
Methods:
Experimental myopia in chicken was induced by form-deprivation. The mRNA in chicken retina was analyzed by using differential display.
Results:
Experimental myopia was successfully induced in chicken through form-deprivation. Differentially expressed gene fragments were detected in retina of chicken with myopic development and recovery as compared with normal controls.
Conclusion:
The differential display of mRNA may be a useful way in cloning myopic-related genes.
