Related Experiment Video
Updated: Aug 9, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
[Analysis of refractive state after excimer laser photorefractive keratectomy in myopia]
1Ophthalmic Laser Center, Xiangya Hospital, HuNan Medical University, Changsha 410078, China.
Objective:
To evaluate refractive state after excimer laser photorefractive keratectomy (PRK) in patients with myopia.
Methods:
234 cases(391 eyes) followed up for two years were divided into two groups, group I: mild and moderate myopia(< or = -6.00 D), 228 eyes; group II: High myopia(> -6.00 D), 163 eyes. The refractive state of patients at three, six, twelve and twenty-four months postoperatively were monitored.
Results:
At two years after photorefractive keratectomy (PRK), refractive regression (> -0.5 D), overcorrection(> 1.00 D), undercorrection(> 1.00 D), postoperative residual astigmatism postoperative astigmatism and hyperopia shift in group I were 1.7%, 4.4%, 5.7%, 12.8%, 7.4% and 7.5% respectively, while in high myopia group were 15.9%, 4.9%, 23.3%, 29.7%, 31.1% and 6.7% respectively.
Conclusion:
The results prove that photorefractive keratectomy is an effective, precise, stable and safe method for correction of mild and moderate myopia, but insufficient for high myopia.

