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Sleep disturbances in Parkinson's disease
1Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Rush Medical College, 1725 West Harrison, Suite 755, Chicago, IL 60612, USA. ccomella@rush.edu
Current Neurology and Neuroscience Reports
|February 14, 2003
Summary
Parkinson's disease frequently causes sleep problems like fragmentation and daytime sleepiness due to symptoms, medications, or other disorders. Effective treatment addresses these underlying causes to improve sleep and alertness.
Area of Science:
- Neurology
- Sleep Medicine
Background:
- Sleep disorders and daytime alertness issues are common in Parkinson's disease (PD).
- These disturbances stem from diverse factors, including PD symptoms, medications, and comorbidities.
Purpose of the Study:
- To review the common sleep disturbances and daytime sleepiness in Parkinson's disease.
- To discuss the contributing factors and diagnostic approaches for these sleep issues.
Main Methods:
- Literature review of sleep disorders in Parkinson's disease.
- Analysis of factors contributing to sleep fragmentation and daytime sleepiness.
Main Results:
- Sleep fragmentation is the most frequent complaint, linked to PD symptoms, medications, nocturia, depression, anxiety, sleep apnea, periodic limb movements, and REM sleep behavior disorder.
- Excessive daytime sleepiness can result from nocturnal sleep deprivation, medications, or central nervous system disruption from PD.
Conclusions:
- Diagnosing sleep disturbances in PD requires patient/caregiver interviews and potential specialist consultation.
- Treatment focuses on identifying and managing causative factors to enhance nocturnal sleep and reduce daytime drowsiness.