Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minimizing Errors in Electron Microprobe Analysis.

Eric Lifshin1, Raynald Gauvin

  • 1New York State Corporate Center for Advanced Thin Film Technology, State University of New York at Albany, Albany, NY.

Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
|February 25, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Crystallographic Effects on Residual Relative Elastic Strain Heterogeneity Induced by Micro-Indentation in Non-Oriented Electrical Steels.

Materials (Basel, Switzerland)·2026
Same author

Dynamical simulation of on-axis transmission Kikuchi and spot diffraction patterns, based on accurate diffraction geometry calibration.

Journal of microscopy·2026
Same author

Valuable mineral materials recovery from Sargassum spp. with a focus on phosphorus as magnesium-whitlockite.

Journal of environmental management·2026
Same author

Comparison of two Monte Carlo approaches for homogeneous bulk samples.

Journal of microscopy·2025
Same author

Nucleation-promoting and growth-limiting synthesis of disordered rock-salt Li-ion cathode materials.

Nature communications·2025
Same author

Combined crystallographic study of king scallop (<i>Pecten maximus</i>) shells using SEM, EBSD and Raman spectroscopy.

Faraday discussions·2025
Same journal

Gradient-Based Experimental Design for Defect Detection in MoS2 Including Emission Potentials for Thermal Diffuse Scattering.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same journal

An Automated Atom Probe Tomography Cluster Detection Approach Using Transfer Learning.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same journal

Correlative Light and Electron Microscopy Visualization of Helicobacter pylori in Human Saliva.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same journal

Integrating Morpho-Anatomy and Histochemistry to Characterize Native Brazilian Eugenia Species.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same journal

Polyalthia Longifolia Induced Apoptosis via miR-484 Downregulation: A Multimodal In Situ Microscopy, In Vitro, and In Vivo Investigation.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same journal

Rhythmic Pattern of the Ovarian Development in Posthatching Japanese Quail (Coturnix coturnix japonica): Histological, Ultrastructural, and Immunohistochemical Study.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
See all related articles

Quantitative electron microprobe analysis errors stem from various factors. Understanding these error sources is crucial for accurate elemental analysis, especially when sample characteristics deviate from standard conditions.

Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Geoscience

Background:

  • Quantitative electron microprobe analysis (QEMPA) is essential for elemental composition determination.
  • Errors in QEMPA can originate from sampling, specimen preparation, instrument operation, data collection, and data analysis.

Purpose of the Study:

  • To assess the relative magnitudes of various error sources in QEMPA.
  • To provide guidelines for developing analytical strategies in QEMPA.
  • To highlight concerns in analyzing even simple systems like NiAl.

Main Methods:

  • Assessment of error sources in quantitative electron microprobe analysis.
  • Analysis of a Nickel-Aluminum (NiAl) sample under standard operating conditions.
  • Demonstration of tools for error assessment.

Related Experiment Videos

Main Results:

  • Identified multiple sources contributing to errors in QEMPA.
  • Quantified the impact of different factors on analytical accuracy for NiAl.
  • Showcased the effectiveness of various error assessment tools.
  • Observed significant error increases when sample characteristics deviate from those used in method development.

Conclusions:

  • Developing a robust analytical strategy requires careful consideration of all potential error sources in QEMPA.
  • Standard operating conditions do not eliminate all sources of error.
  • Deviations in sample characteristics from established methods can substantially amplify analytical inaccuracies.