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Design and synthesis of potent N1-substituted indole melatonin receptor agonists
Andrew Tsotinis1, Andreas Eleutheriades, Katherine Hough
1Department of Pharmaceutical Chemistry, School of Pharmacy, University of Athens, Panepistimiopolis-Zografou, 157 71, Athens, Greece. tsotinis@pharm.uoa.gr
Abstract:
The design and expeditious synthesis of two new indole analogs with up to 5-fold potency of that of melatonin is described.