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The Slice Culture Method for Following Development of Tooth Germs In Explant Culture
Published on: November 13, 2013
Study on tooth development, past, present, and future
Han-Sung Jung1, Yamamoto Hitoshi, Hee-Jin Kim
1Department of Oral Biology, College of Dentistry, Institute of Life Science and Biotechnology, Brain Korea 21 Project of Medical Sciences, Yonsei University, Seoul, Korea. hsjung@yumc.yonsei.ac.kr
Abstract:
For decades, the understanding of craniofacial development has been a central issue in odontology and developmental biology. As a consequence, a significant number of deformities are being studied for their variety of genotype and phenotype. Although there is little doubt about the essential roles of homeobox genes, transcription factors, and growth factors, we now know at least the fundamental strategy of craniofacial biology. The tooth as an organ performs a whole range of functions, each of which is truly indispensable for the maintenance of life. The possession of teeth is, therefore, obviously coupled with the complication of the natural structure of an individual organism. In the following, we shall focus on a brief history of tooth studies and some suggestions for obtaining a full understanding of teeth in the future.
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