Oral manifestations of systemic disease
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Updated: Sep 27, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Edwin T Parks1, Henry Lancaster
1Department of Oral Pathology, Medicine, and Radiology, Indiana University School of Dentistry, West Michigan Street, Indianapolis, IN 46202, USA. edparks@iupui.edi
Abstract:
Most systemic diseases can affect the oral cavity. Some oral changes are nonspecific, whereas others directly lead to the diagnosis of a particular disorder. A systems approach is used here to catalog these oral changes. In some instances it is difficult to separate the oral manifestations of pharmacotherapy for a particular disease from that entity. The oral manifestations of pharmacotherapy are presented for selected disease processes. This article introduces the most common oral manifestations of systemic disease.
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