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Do hemoglobin and hemocyanin impair schistosoma killing by no?
Paolo Ascenzi1, Mauro Fasano, Luigi Gradoni
1Dipartimento di Biologia, Università Roma Tre, Roma, Italy. ascenzi@bio.uniroma3.it
IUBMB Life
|March 11, 2003
Abstract:
Nitric oxide (NO) possesses antiparasitic effects on both Protozoa and Metazoa in definitive and intermediate hosts as well as in vectors. Here, we postulate that hemoglobin and hemocyanin may impair Schistosoma killing by NO in the definitive and intermediate hosts. Interestingly, hemoglobin, myoglobin, and neuroglobin may protect Plasmodium and Trypanosoma from the antiparasitic effects of NO.