[Preliminary investigation on the relation between clinical progress and anti-small monomolecular peptides antibody in individual infected with HIV]
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Updated: Sep 26, 2026
Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
Published on: September 14, 2014
Xiaoyuan Xu1, Huichun Xing, Weibo Gong
1Department of Infectious Diseases, the First Hospital, Beijing University, Beijing 100034,China.
Objective:
To study the quantity of anti-R7V in individuals infected with HIV and AIDS patients and its relation with the progression of disease.
Methods:
ELISA and precipitation and other methods were used to investigate the quantity of anti-R7V in asymptomatic long-term survivors and AIDS patients.
Results:
Positive rate and quantity of anti-R7V were higher in the HIV active ones and AIDS. It showed that the quantity and positive rate of anti-R7V were rather high in dissolving test.
Conclusions:
It is strong suggestion for anti-R7V to obstruct the replication of virus by interfering the connection between HIV with CCR5 or CXCR4 and so it impossible HIV entering to CD4+ T cells.
