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Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
Published on: December 14, 2015
Wnts as morphogens? The view from the wing of Drosophila
1Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. ama11@cus.cam.ac.uk
Nature Reviews. Molecular Cell Biology
|April 3, 2003
Abstract:
Morphogens are diffusible signalling molecules that pattern cellular fields by setting up differential gene expression in a concentration-dependent manner. Members of the Wnt family of signalling molecules are generally considered to be classical morphogens. However, a close analysis of their activity indicates that they do not fulfil all of the critera that are associated with the classical definition.
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