Related Experiment Videos
[Ability of cipramil to correct conditioned passive avoidance in ovariectomized female rats]
1Department of Neuropharmacology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, ul. akademika Pavlova Str, 12, St. Petersburg, 197376 Russia.
Eksperimental'Naia I Klinicheskaia Farmakologiia
|April 10, 2003
Abstract:
The ability of cypramil, a selective inhibitor of serotonin re-uptake, to modify the cognitive performance was studied in ovariectomized female rats with passive avoidance paradigm and in the open-field test. It was found that cypramil in combination with estradiol restored the formation and retention of the passive avoidance performance. In addition, cypramil improved the emotional component of behavior in the open-field test.