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Effect of Surfagon on Open Field and Elevated Plus Maze Behavior of Gonadectomized and Non-Gonadectomized Male Rats
O O Masalova1, S B Kazakova2, T N Savateeva-Lyubimova2
1Institute of Experimental Medicine, Ministry of Health of the Russian Federation, St. Petersburg, Russia. o.o.masalova@gmail.com.
Bulletin of Experimental Biology and Medicine
|November 20, 2019
Abstract:
We studied the effect of gonadotropin-releasing hormone agonist surfagon (2 μg/kg, once, intraperitoneally) on anxious behavior of adult gonadectomized and non-gonadectomized male rats. It was shown that surfagon significantly increased anxiety of both gonadectomized and non-gonadectomized rats in the open-field test and in elevated plus maze.
