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Pasteurella multocida aortic valve endocarditis: case report and literature review
Georges Fayad1, Thomas Modine, Samia Mokhtari
1Service de chirurgie cardiovasculaire, Hopital cardiologique, CHRU de Lille, France.
The Journal of Heart Valve Disease
|April 19, 2003
Summary
Pasteurella multocida rarely causes infective endocarditis, especially in immunocompromised individuals. This case highlights a patient with liver cirrhosis who developed P. multocida aortic valve endocarditis, requiring valve replacement and antibiotic treatment.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Pasteurella multocida is an uncommon pathogen causing infective endocarditis, typically seen in immunocompromised patients.
- Infective endocarditis carries a high mortality rate, particularly when caused by unusual organisms.
Observation:
- A 48-year-old male with liver cirrhosis presented with symptoms suggestive of meningitis and a diastolic murmur.
- Blood cultures identified Pasteurella multocida as the causative agent of aortic valve endocarditis.
- Transthoracic echocardiography revealed a large aortic valve vegetation and significant insufficiency.
Findings:
- Surgical intervention included aortic valve replacement with a bioprosthetic valve.
- The patient experienced a recurrent episode of endocarditis, successfully managed with antibiotics.
- Review of literature indicates P. multocida endocarditis is rare and associated with significant morbidity.
Implications:
- This case underscores the importance of considering P. multocida in endocarditis, even in non-immunocompromised patients.
- Early diagnosis and appropriate management, including surgical intervention and antibiotics, are crucial for favorable outcomes.
- Further research into P. multocida endocarditis pathogenesis and treatment strategies is warranted.