[Effect of bifidobacteria on the anti-lysozyme activity of enterobacteria]

The influence of the subinhibitory concentrations of bifidobacterial exometabolites on the capacity for inactivating lysozyme in pathogenic and opportunistic enterobacteria was determined. The supernatant of B. bifidum 1 suppressed antilysozyme activity (ALA) in most Klebsiella strains and in some pathogenic Escherichia coli strains, but increased ALA in some E. coli of indigenous flora and failed to influence ALA in Salmonellae. The stimulating effect of the vital activity products of bifidobacteria with respect to the antilysozyme sign in some S. enteritidis isolates and diarrheagenic E. coli was found. These properties should be taken into consideration while selecting strains for the construction of probiotics.