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Three cases of advanced seminoma and Down's syndrome: a possible association
Diana C Hsiung Stripp1, David Vaughn, Keith Van Arsdalen
1Department of Radiation Oncology, Hospital of the University of Pennsylvania, 2 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, U.S.A.
American Journal of Clinical Oncology
|April 26, 2003
Abstract:
This is a report of three cases of classic seminoma in Down's syndrome patients treated at our institution. Review of literature shows an observation of increased occurrence of testicular cancer in patients with DS, however, with no definitive association documented. A brief discussion of the possible pathogenesis is presented.