Bone disorders, hypertension, and mitochondrial toxicity in HIV disease

Osteonecrosis, osteopenia and osteoporosis, hypertension, and mitochondrial toxicity are among the medical conditions observed in patients with HIV disease. In some cases, these disorders have been associated with antiretroviral therapy or particular antiretroviral agents. In other cases, their etiology remains unclear. Meg D. Newman, MD, discussed data from studies of these conditions and current management approaches at the Clinical Pathway of the Ryan White CARE Act 2002 All Grantee Conference held in Washington, DC, in August 2002.