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Cytotoxic effect of low-density lipoproteins
V A Nagornev1, A N Voskan'yants, A G Vinogradov
1Research Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg. van@iem.spb.ru
Bulletin of Experimental Biology and Medicine
|April 30, 2003
Abstract:
The cytopathogenic effect of various modified lipoproteins on cultured peritoneal macrophages was studied in vitro. After minor peroxide modification lipoproteins induced apoptosis of macrophages. Immune complexes containing oxidized lipoproteins caused cell necrosis.