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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
[HIV infection in the Stavropol' region]
N G Filonenko1, V P Isaev, N L Pelikh
1Territorial Center for the Prophylaxis and Control of AIDS, Stavropol, Russia.
Abstract:
The data on the dynamics of HIV infection in the Stavropol Territory beginning with 1987 are given. The situation became aggravated after 1996, and its sharp deterioration occurred in 2000 when 138 cases of HIV infection were detected and the area of this infection increased. In most cases patients became infected beyond the borders of the territory. About a half of the new cases of HIV infection registered in 2000 were detected in Ingushetia and Chechnya. The leading factor in the spread of HIV infection was the use of drugs by injection. The main trends of the prophylactic work are presented.
Insights
HIV infection dynamics in Stavropol Territory worsened significantly after 1996, peaking in 2000. Drug injection was the primary driver, with many infections originating outside the region.
Area of Science:
- Epidemiology
- Public Health
Context:
- The Stavropol Territory has tracked HIV infection dynamics since 1987.
- A notable increase in HIV cases occurred after 1996, with a sharp rise in 2000.
- A significant proportion of infections were acquired outside the region, particularly in Ingushetia and Chechnya.
Purpose:
- To analyze the epidemiological trends of HIV infection in the Stavropol Territory.
- To identify the primary risk factors and geographical origins of HIV transmission.
Summary:
- Data from 1987 onwards reveal an escalating HIV epidemic in Stavropol.
- The year 2000 marked a critical point with 138 new cases and expanded geographical spread.
- Intravenous drug use was identified as the main transmission route.
- Cross-border infections, especially from Ingushetia and Chechnya, contributed substantially to the caseload.
Impact:
- Highlights the critical role of drug injection in HIV spread.
- Underscores the need for regional cooperation in HIV prevention and control.
- Informs targeted public health interventions for high-risk populations and geographical areas.
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