Renewing the debate over the p53 apoptotic response

An identical, complex TP53 mutation arising independently in two unrelated families with diverse cancer profiles: the complexity of interpreting cancer risk in carriers.

Oncogenesis·2013

The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation.

Oncogene·2013

Genetically defining the mechanism of Puma- and Bim-induced apoptosis.

Cell death and differentiation·2011

Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.

Oncogene·2010

Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.

Oncogene·2009

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

Cell death and differentiation·2009

DHRS9 generates crotonyl-CoA from butyryl-CoA to epigenetically regulate STING transcription and potentiate immune activation.

Cell death and differentiation·2026

Repurposing BH3 mimetics to deplete tumour-infiltrating regulatory T cells and enhance anti-tumour immunity in non-small cell lung cancer.

Cell death and differentiation·2026

PAD4-generated citrullinated histones are triggers for autoinflammation in cryopyrin-associated periodic syndrome.

Cell death and differentiation·2026

Targeting POLRMT-driven epigenetic remodeling of Wnt/β-catenin to eradicate colorectal cancer stem cell proliferation.

Cell death and differentiation·2026

ZDHHC8-mediated S-palmitoylation of RAD21 causes mitochondrial dysfunction in diabetic nephropathy via inhibiting ACSM3 transcription.

Cell death and differentiation·2026

Targeting of Gpx8-CSF1 axis resets the immune milieu of lung tumor and overcomes resistance to anti-PD-1 therapy.

Cell death and differentiation·2026

A four-factor model of psychopathy assessed via neural reinforcement sensitivity theory.

Personality neuroscience·2026

Polycomb-Derived Posttraumatic Stress Disorder (PTSD) Signals Diverge From Classical Aging Pathways and Converge on Neuroimmune Genes.

Cureus·2026

Psilocybin's effect on human brain synaptic plasticity.

Translational psychiatry·2026

Neuroimaging findings in extrasensory perception research: A PRISMA-informed descriptive synthesis.

Explore (New York, N.Y.)·2026

Autonomic-anxiety symptoms of dysfunctional breathing in females with low back pain: A Nijmegen questionnaire-based secondary analysis in primary care.

Journal of back and musculoskeletal rehabilitation·2026

Behavioral Procrastination and Heart Age Acceleration in a Large Occupational Cohort.

Journal of clinical medicine·2026

Related Experiment Videos

Renewing the debate over the p53 apoptotic response

Related Concept Videos

An identical, complex TP53 mutation arising independently in two unrelated families with diverse cancer profiles: the complexity of interpreting cancer risk in carriers.

The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation.

Genetically defining the mechanism of Puma- and Bim-induced apoptosis.

Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.

Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

DHRS9 generates crotonyl-CoA from butyryl-CoA to epigenetically regulate STING transcription and potentiate immune activation.

Repurposing BH3 mimetics to deplete tumour-infiltrating regulatory T cells and enhance anti-tumour immunity in non-small cell lung cancer.

PAD4-generated citrullinated histones are triggers for autoinflammation in cryopyrin-associated periodic syndrome.

Targeting POLRMT-driven epigenetic remodeling of Wnt/β-catenin to eradicate colorectal cancer stem cell proliferation.

ZDHHC8-mediated S-palmitoylation of RAD21 causes mitochondrial dysfunction in diabetic nephropathy via inhibiting ACSM3 transcription.

Targeting of Gpx8-CSF1 axis resets the immune milieu of lung tumor and overcomes resistance to anti-PD-1 therapy.

A four-factor model of psychopathy assessed via neural reinforcement sensitivity theory.

Polycomb-Derived Posttraumatic Stress Disorder (PTSD) Signals Diverge From Classical Aging Pathways and Converge on Neuroimmune Genes.

Psilocybin's effect on human brain synaptic plasticity.

Neuroimaging findings in extrasensory perception research: A PRISMA-informed descriptive synthesis.

Autonomic-anxiety symptoms of dysfunctional breathing in females with low back pain: A Nijmegen questionnaire-based secondary analysis in primary care.

Behavioral Procrastination and Heart Age Acceleration in a Large Occupational Cohort.

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Renewing the debate over the p53 apoptotic response

Related Concept Videos

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