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Trypsin inhibitory effect of wedelolactone and demethylwedelolactone
Samiulla D Syed1, Mundkinajeddu Deepak, Shivanna Yogisha
1Bioassay Unit, R&D Centre, Natural Remedies Pvt Ltd, 5B, Veerasandra Indl Area, Hosur Road, Bangalore 561 229, India.
Phytotherapy Research : PTR
|May 2, 2003
Abstract:
Wedelolactone (WL) and demethylwedelolactone (DWL) isolated from Eclipta alba were tested in the trypsin inhibition bioassay (in vitro). Both compounds showed potent activity. IC(50) values of WL and DWL were found to be 2.9 and 3.0 microg/mL respectively.