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Acute flaccid paralysis from echovirus type 33 infection

Keith Grimwood1, Q Sue Huang, Lynette G Sadleir

  • 1Department of Paediatrics and Child Health, Wellington School of Medicine and Health Sciences, New Zealand. grimwood@wnmeds.ac.nz

Journal of Clinical Microbiology
|May 8, 2003
PubMed

Insights

Echovirus type 33 infection was linked to acute flaccid paralysis in a child during a community outbreak. This is the first reported association between this virus and paralysis.

Area of Science:

  • Virology
  • Neurology
  • Pediatrics

Background:

  • Echoviruses are common viruses that can cause a range of illnesses.
  • Acute flaccid paralysis (AFP) is a serious condition that can lead to permanent disability.

Observation:

  • During a community outbreak, a 3-year-old boy presented with right arm weakness after a mild febrile illness.
  • Echovirus type 33 was detected in the boy's feces and cerebrospinal fluid.

Findings:

  • This case represents the first reported association between echovirus type 33 infection and acute flaccid paralysis.
  • The findings suggest echovirus type 33 as a potential cause of AFP.

Implications:

  • This discovery expands the known spectrum of echovirus type 33-associated diseases.
  • Further research is warranted to understand the mechanisms and prevalence of echovirus type 33-induced AFP.
  • Public health surveillance for echovirus type 33 should consider its potential role in AFP cases.

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