Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Characterization of trabecular bone using the backscattered spectral centroid shift.

Keith A Wear1

  • 1U.S. Food and Drug Administration, Center for Devices and Radiological Health, Rockville, MD 20852, USA. kaw@cdrh.fda.gov

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
|May 15, 2003
PubMed
Summary

Ultrasonic attenuation in bone can be measured using backscattered signals. This new method shows promise for assessing bone health at sites like the hip and spine, potentially improving fracture risk prediction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch.

Nature biotechnology·2026
Same author

Blood-mimicking dye phantoms for evaluating photoacoustic oximetry accuracy.

Photoacoustics·2026
Same author

Erratum to 'A 15-Min Method for Hydrophone Spatial Averaging Correction in Transcranial Neuromodulation System Characterization'[Ultrasound in Medicine & Biology 52 (2026) 254-258].

Ultrasound in medicine & biology·2025
Same author

A 15-Min Method for Hydrophone Spatial Averaging Correction in Transcranial Neuromodulation System Characterization.

Ultrasound in medicine & biology·2025
Same author

Spatial Resolution Limits for Needle Hydrophones From 0.5 to 20 MHz With Implications for Transcranial Ultrasound.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2025
Same author

Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2024

Area of Science:

  • Biomedical Engineering
  • Orthopedics
  • Medical Imaging

Background:

  • Ultrasonic attenuation in bone is a key indicator for osteoporotic fracture risk.
  • Current methods (through-transmission) are limited to specific sites like the calcaneus.
  • Measurements at hip and spine are challenging due to anatomical complexity and soft tissue.

Purpose of the Study:

  • To investigate the feasibility of using backscattered ultrasound signals to assess bone attenuation.
  • To evaluate centroid shift as an index for bone attenuation slope.
  • To explore potential applications for assessing bone health at clinically relevant sites beyond the calcaneus.

Main Methods:

  • In vitro measurement of centroid shift from backscattered ultrasound signals from 30 trabecular bone samples.

Related Experiment Videos

  • Measurement of attenuation slope using a conventional through-transmission method.
  • Correlation analysis between centroid shift and attenuation slope.

    • Main Results:

    • A strong negative correlation (r = -0.71) was found between centroid shift and attenuation slope.
    • The 95% confidence interval for the correlation was (-0.86, -0.47).
    • This indicates centroid shift is a reliable indicator of bone attenuation.

    Conclusions:

    • Backscattered spectral centroid shift shows potential as a non-invasive method for assessing bone attenuation.
    • This technique may offer a viable alternative for evaluating bone health at the hip and spine.
    • Further research could lead to improved diagnostic tools for osteoporosis and fracture risk assessment.