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Burkitt-like lymphoma in an infant: a case report

Claudete Esteves Klumb1, Lídia Maria Magalhães de Resende, Claudio Gustavo Stefanoff

  • 1Cancer Hospital, National Institute of Cancer, Rio de Janeiro, Brazil.

Revista Do Hospital Das Clinicas
|May 20, 2003
PubMed

Insights

Pediatric non-Hodgkin

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Immunology

Background:

  • Non-Hodgkin's lymphomas are uncommon in infants.
  • Burkitt and Burkitt-like lymphomas are rare pediatric malignancies.

Observation:

  • A 13-month-old infant presented with extensive abdominal disease, ascites, and pleural effusion.
  • Tumor lysis syndrome was also observed in the patient.

Findings:

  • A B-cell lymphoma was diagnosed, characterized by a germinal center B-cell phenotype.
  • Polymerase chain reaction confirmed B-cell clonality.
  • Epstein-Barr virus and HIV infections were ruled out.

Implications:

  • This case highlights the importance of considering lymphoma in infants.
  • Early diagnosis of pediatric lymphoma is crucial for timely intervention.
  • Further research into rare infant lymphomas may improve diagnostic and treatment strategies.

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