[Severe forms of acne with unusual clinical courses]

In two cases we could demonstrate the complications, which might appear in the clinical course of severe forms of juvenile acne. Our first case deals with a young male patient with leukaemic reaction in his peripheral blood and bone-marrow (sternal puncture) and excessively raised erythrocyte-sedimentation-rate, who developed bilateral ileo-sacral-fusion arthritis. The second case dealt with a young female patient with spondylitis and an enormously raised erythrocyte-sedimentation-rate.