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Preventive strategy to control iron deficiency anemia in children and adults

I A Siddiqui1, A Jaleel, M A Rahman

  • 1Department of Biochemistry, Ziauddin Medical University, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|June 5, 2003
PubMed

Insights

Weekly iron supplementation significantly improved hemoglobin and ferritin levels in children and women. This approach is more effective for managing iron deficiency anemia due to better compliance and cost-effectiveness.

Area of Science:

  • Hematology
  • Nutritional Science
  • Public Health

Background:

  • Iron deficiency anemia is a prevalent global health issue, particularly affecting children and women of reproductive age.
  • Oral ferrous sulfate is a common treatment, but compliance and efficacy can be challenging with daily dosing.

Purpose of the Study:

  • To compare the efficacy of daily versus weekly oral ferrous sulfate supplementation.
  • To evaluate improvements in key hematological parameters (hemoglobin, MCV, MCH, ferritin).
  • To assess supplementation in pediatric (5-10 years) and reproductive-age female (15-45 years) populations.

Main Methods:

  • Children (n=40) received 200 mg ferrous sulfate daily or weekly for two months.
  • Women (n=30) received 300 mg daily, 300 mg weekly, or 600 mg weekly for one month.
  • Hematological parameters were measured to assess treatment response.

Main Results:

  • Significant improvements in hemoglobin, MCV, MCH, and ferritin were observed in children with both daily and weekly ferrous sulfate.
  • Women showed significant parameter improvements with daily 300 mg and weekly 600 mg ferrous sulfate doses.
  • Weekly supplementation demonstrated comparable or superior results in certain groups.

Conclusions:

  • Weekly iron supplementation is a viable and effective strategy for managing iron deficiency anemia.
  • The cost-effectiveness and improved patient compliance associated with weekly dosing make it a preferable public health approach.
  • Further research may optimize weekly dosing regimens for diverse populations.
Abstract

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