[Functional significance of alpha- and beta-adrenoreceptors in structures of the stropallidal system]

Microapplication of noradrenaline, isadrine, phentolamine, and propranole to neuroanal populations of the striatum in curarized unanesthetized rabbits revealed an inhibitory and stimulatory effects of noradrenaline and isadrine. A specific antagonism between alpha- and beta-adrenomimetics and respective alpha- and beta-adrenoblocking agents, was noted. Noradenaline seems to have a very important mediatory function in the adrenergic synapases of the striatum. Existence of alpha- and beta-adrenoreceptors with different functions in different brain areas, is suggested.