Related Experiment Video
Updated: Aug 9, 2026

Intravenous Injections in Neonatal Mice
Published on: November 11, 2014
[Intravenous inmunoglobulins in pediatrics]
M I Panadero Esteban1, J Carcelén Andrés, E Urbieta Sanz
1Servicio de Farmacia, Hospital Montepríncipe, Hospital Universitario Miguel Servet. Zaragoza. Spain.
Abstract:
The use of intravenous immunoglobulins remains controversial after their introduction in therapeutics during the 80s. Their mechanism of action remains unexplained for certain pathologies, but their application to new indications and their economical impact makes them a target of many studies and protocols of use. Intravenous immunoglobulins are administred as substitution therapy in primary and secondary immunodeficiencies. On the other hand, their immunomodulating effect is the basis of their use on a great variety of autoimmune diseases and inflammatory processes, although not always following the authorised indications. This study reviews the use of intravenous immunoglobulins in pediatric population, making the distinction between the indications authorised by the regulatory authorities, and those non-authorised but supported by scientific publications.
Related Concept Videos
Routes of Drug Administration: Parenteral
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Distribution
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

