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Evolution from semi-tRNA to tRNAs, rRNAs and an early peptide-synthesizing RNA molecule
1Department of Biology, Faculty of Science, Niigata University, Japan.
Nucleic Acids Symposium Series
|January 1, 1992
Abstract:
tRNA was found to have emerged by tandem duplication of a ca. 37-base RNA ("semi-tRNA"). The most ancestral anticodon was "(5')CCA(3')". The peptidyltransferase (PT) region of 23S rRNA was concluded to be a 5S rRNA homologue. Important evidences were obtained for elucidating that the RNA transcript from the Bacillus subtilis (BSU) trrnD operon is a relic of an early peptide-synthesizing ribozyme.