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The first examples of ring-closing olefin metathesis of vinyl chlorides
Wenchun Chao1, Steven M Weinreb
1Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Organic Letters
|July 5, 2003
Abstract:
[reaction: see text] Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected by using the second generation Grubbs catalyst (10 mol %, PhH, 65 degrees C) to produce a variety of carbocyclic and heterocyclic five-, six-, and seven-membered rings in excellent yields.