Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene

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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
11:13

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Published on: April 10, 2018

S Arnaud-Dabernat1, P M Bourbon, A Dierich

  • 1Biologie de la Différenciation et du Développement, Université Victor Segalen-Bordeaux2, Bordeaux, France.

Journal of Bioenergetics and Biomembranes
|July 10, 2003
PubMed

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...