Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Narcolepsy01:07

Narcolepsy

466
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
466
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.9K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.9K
Amnesia01:13

Amnesia

427
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
427
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K
Dementia01:30

Dementia

487
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
487

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current and future suitability of wintering grounds for a long-distance migratory raptor.

Scientific reports·2017
Same author

Photoperiodic response to early hatching in a migratory bird species.

Oecologia·2017
Same author

Ecophysiological aspects of rapid population growth in a novel migratory blackcap (Sylvia atricapilla) population: an experimental approach.

Oecologia·2017
Same author

[A comparative study of diurnal patterns of activity and diurnal changes of body weight in caged and free-living warblers (sylvia)].

Oecologia·2017
Same author

Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods.

Artificial DNA, PNA & XNA·2012
Same author

The bacterial microbiota in the ceca of Capercaillie (Tetrao urogallus) differs between wild and captive birds.

Systematic and applied microbiology·2011
Same journal

Contemporary Oral and Maxillofacial Trauma: A Dental Perspective.

Dental clinics of North America·2026
Same journal

The Expanding Role of Virtual Surgical Planning in Maxillofacial Trauma Management.

Dental clinics of North America·2026
Same journal

Revision Surgery for Occlusal Correction in Facial Trauma.

Dental clinics of North America·2026
Same journal

Mandibular Condylar Fractures and Occlusal Management.

Dental clinics of North America·2026
Same journal

Occlusion Management in Facial Trauma: A Literature Review.

Dental clinics of North America·2026
Same journal

Dental Implants in Rehabilitation of Patients with Facial Trauma: a Review of Most Current Practices.

Dental clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jan 10, 2026

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
07:04

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans

Published on: August 15, 2020

5.8K

Noma: a forgotten disease.

Peter Berthold1

  • 1Department of Community Oral Health, University of Pennsylvania School of Dental Medicine, WHO Collaborating Center, 240 South 40th Street, Philadelphia, PA 19104, USA. berthold@pobox.upenn.edu

Dental Clinics of North America
|July 10, 2003
PubMed
Summary
This summary is machine-generated.

Noma, a severe oral disease affecting impoverished children in sub-Saharan Africa, is increasing. Early intervention with antibiotics and supportive care can halt noma, but delayed treatment leads to high mortality and severe facial deformities.

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.2K
Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

12.2K

Related Experiment Videos

Last Updated: Jan 10, 2026

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
07:04

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans

Published on: August 15, 2020

5.8K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.2K
Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

12.2K

Area of Science:

  • Global Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Noma (cancrum oris) is an ancient, destructive disease primarily affecting impoverished children in sub-Saharan Africa.
  • The incidence of noma is reportedly increasing, often following measles or other debilitating illnesses.
  • The disease progresses rapidly from oral ulcers to extensive facial necrosis.

Purpose of the Study:

  • To summarize the current understanding of noma's increasing prevalence and impact.
  • To highlight the critical need for early diagnosis and intervention in noma cases.
  • To outline the World Health Organization's (WHO) Action Network Against Noma initiatives.

Main Methods:

  • Review of recent World Health Organization (WHO) reports on noma prevalence.
  • Analysis of noma's clinical presentation, progression, and contributing factors.
  • Examination of the WHO's established five-point action plan for noma control.

Main Results:

  • Noma is a growing public health concern, particularly in resource-limited settings.
  • Early treatment involving antibiotics, rehydration, and nutritional support is crucial for survival.
  • High mortality rates underscore delayed access to or lack of timely medical care.

Conclusions:

  • Prompt medical intervention is essential to prevent noma's devastating consequences, including high mortality and severe facial disfigurement.
  • Survivors often require extensive reconstructive surgery due to extensive tissue damage.
  • The WHO's Action Network Against Noma provides a framework for global efforts to combat this disease.