Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary function tests in preschool children with asthma.

Nicole Beydon1, Isabelle Pin, Régis Matran

  • 1Physiology Department of the Robert Debré Teaching Hospital, Grenoble, France.

American Journal of Respiratory and Critical Care Medicine
|July 19, 2003
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A three-year randomized, double-blind, placebo-controlled study of lanreotide in stage 2/3 autosomal dominant polycystic kidney disease.

Kidney international·2026
Same author

Tobacco and cannabis use in the young 'Not in Employment, Education or Training' population: A systematic review and meta-analysis.

Addiction (Abingdon, England)·2026
Same author

Home CPAP/NIV in pediatric patients: which disorders?

Sleep medicine·2026
Same author

Current Practices and a Novel Operational Framework for Planning Research on Digital Health Promotion Interventions From Development to Implementation: Scoping Review.

Journal of medical Internet research·2026
Same author

Functional assessment of a convergent gene network underlying allergic diseases and IgE.

The Journal of allergy and clinical immunology·2026
Same author

Prophylactic Treatment of Patent Ductus Arteriosus With Acetaminophen: A Randomized Clinical Trial.

JAMA pediatrics·2026

Pulmonary function tests reveal preschool children with asthma have higher airway resistance. These tests, using the interrupter technique, aid asthma management in young children unable to perform standard lung function tests.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Physiology

Background:

  • Pulmonary function tests (PFTs) are rarely conducted in preschool children diagnosed with asthma.
  • Assessing lung function in this age group is challenging due to their inability to perform forced expiratory maneuvers.

Purpose of the Study:

  • To compare pulmonary function parameters between preschool children with asthma and healthy controls.
  • To evaluate the utility of non-cooperative PFTs for asthma diagnosis and management in young children.

Main Methods:

  • A multicenter study involving 74 preschool children with asthma and 84 healthy controls (height 90-130 cm).
  • Measurements included functional residual capacity (helium dilution) and expiratory interrupter resistance (interrupter technique).
  • Bronchodilator response was assessed by measuring changes in resistance.

Related Experiment Videos

Main Results:

  • Children with asthma exhibited significantly higher airway resistance and lower specific expiratory interrupter conductance compared to controls.
  • Higher resistance was observed in asthmatic children with exertional symptoms.
  • Asthmatic children showed a significantly greater bronchodilator response in resistance compared to controls.

Conclusions:

  • Non-cooperative PFTs, specifically the interrupter technique, can differentiate pulmonary function in preschool children with asthma.
  • These tests offer a valuable tool for the management and follow-up of asthma in young children unable to perform traditional PFTs.