Related Experiment Video
Updated: Aug 10, 2026

05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
[Trabeculectomy combined with mitomycin C and removed suture in glaucoma]
1Department of Ophthalmology, 3rd Affiliated Hospital, Guangdong Medical College, Maoming 525011, China.
Yan Ke Xue Bao = Eye Science
|July 23, 2003
Summary
Trabeculectomy with Mitomycin C significantly reduced postoperative complications like low intraocular pressure (IOP) and shallow anterior chambers in glaucoma patients. This surgical approach is recommended for glaucoma treatment.
Area of Science:
- Ophthalmology
- Surgical Innovation
Background:
- Glaucoma poses a significant risk to vision due to elevated intraocular pressure (IOP).
- Trabeculectomy is a standard surgical procedure for glaucoma management.
- Mitomycin C is an antifibrotic agent used to enhance surgical outcomes.
Purpose of the Study:
- To evaluate the clinical efficacy of trabeculectomy combined with Mitomycin C and suture removal.
- To compare the outcomes of this combined approach against standard trabeculectomy.
Main Methods:
- A randomized controlled trial involving 75 patients (99 eyes) with glaucoma.
- Patients were divided into two groups: standard trabeculectomy (control) and trabeculectomy with Mitomycin C (observed).
- Key metrics included intraocular pressure (IOP), anterior chamber depth, filtering bleb appearance, visual acuity, and complications.
Main Results:
- The observed group showed a lower incidence of postoperative hypotony (low IOP) and shallow anterior chambers.
- Fewer instances of visual acuity loss and other ocular complications were noted in the observed group.
- Trabeculectomy with Mitomycin C demonstrated improved safety and efficacy.
Conclusions:
- Trabeculectomy, particularly when enhanced with Mitomycin C, effectively controls aqueous humor outflow.
- This surgical technique significantly reduces the incidence of postoperative complications.
- The combined approach is a valuable and recommended option for glaucoma surgery.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

